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1-((3,5-Difluorophenyl)sulfonyl)bicyclo[1.1.0]butane

ALDRICH/ALD00558 - 95%

Synonym: Baran cyclobutylation reagent

Empirical Formula (Hill Notation): C10H8F2O2S
Molecular Weight: 230.23
Linear Formula: C10H8F2O2S
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-ALD00558-500MG 500 mg
 $480.00
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assay 95%
form powder or crystals
Quality Level 100 
reaction suitability reaction type: C-C Bond Formation
storage temp. 2-8°C
Application: The following "spring-loaded" electrophile is a convenient reagent for the installation of cyclobutane to primary and secondary amines. This product is one of several synthetically useful reagents reported by Baran  and coworkers on strain-release amination .
General description: 1-((3,5-Difluorophenyl)sulfonyl)bicyclo[1.1.0]butane can be used as a cyclobutylation agent to introduce bicyclobutane group onto a variety of amines and thiols without affecting other functional groups.
Packaging: 500 mg in glass bottle
RIDADR NONH for all modes of transport
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Purity 95%
Storage Temp. 2-8°C
UNSPSC 12352101

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