1,4,7,10-Tetraazacyclododecane-1,4,7,10-tetraacetic acid
ALDRICH/86734 - ≥97.0% (CHN)
Synonym: DOTA
CAS Number: 60239-18-1
Empirical Formula (Hill Notation): C16H28N4O8 · xH2O
Molecular Weight: 404.42 (anhydrous basis)
MDL Number: MFCD00068657
Linear Formula: C16H28N4O8 · xH2O
Product Type: Chemical
| assay | ≥97.0% (CHN) |
| form | powder |
| functional group | carboxylic acid |
| InChI | 1S/C16H28N4O8/c21-13(22)9 |
| InChI key | WDLRUFUQRNWCPK-UHFFFAOYSA |
| Quality Level | 100 ![]() |
| SMILES string | OC(=O)CN1CCN(CCN(CCN(CC1) |
| Application: | 1,4,7,10-Tetraazacyclodod • It has been used for radiolabeling of carbon nanotube bioconjugates by chelating 64Cu radioisotope. • DOTA can be activated with N-hydroxysulfosuccinimidyl for conjugation with monoclonal antibodies in clinical radioimmunotherapy. • It can form complexes with gadolinium for application as MRI contrast agents. • Metal complexes of DOTA-peptide conjugates can be used as therapeutic radiopharmaceuticals. |
| Packaging: | 50, 250 mg in poly bottle |
| Hazard Codes | Xi |
| Risk Statements | 36/37/38 |
| Safety Statements | 26-36 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥97.0% (CHN) |
| UNSPSC | 12352005 |

