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Methacrylic acid N-hydroxysuccinimide ester

ALDRICH/730300 - 98%

Synonym: N-(Methacryloxy)succinimide; N-(Methacryloyloxy)succinimide

CAS Number: 38862-25-8
Empirical Formula (Hill Notation): C8H9NO4
Molecular Weight: 183.16
MDL Number: MFCD15072193
Linear Formula: C8H9NO4
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-730300-1G 1 g
 $102.00
1/EA		 Add To Favorites
45-730300-5G 5 g
 $339.00
1/EA		 Add To Favorites

 

assay 98%
form solid
InChI 1S/C8H9NO4/c1-5(2)8(12)13-9-6(10)3-4-7(9)11/h1,3-4H2,2H3
InChI key ACGJEMXWUYWELU-UHFFFAOYSA-N
mp 101-105 °C
Quality Level 100 
SMILES string CC(=C)C(=O)ON1C(=O)CCC1=O
storage temp. 2-8°C
Application: Methacrylic acid N-hydroxysuccinimide ester can be used:• As a monomer to prepare degradable amphiphilic diblock copolymer microparticles via RAFT polymerization, for low pH-triggered drug delivery. NHS-MA can shield the drug molecule from degradation, enhance its solubility, and improve its pharmacokinetic properties.
• For the surface functionalization of poly-ε-caprolactone (PCL) scaffolds used for tissue engineering. NHS groups are used to couple with chitosan of various molecular weights.
• To prepare biocompatible polymer hydrogel for enzymatic biofuel cells. The hydrogel can serve as an enzyme-immobilizing matrix for enzymatic bioelectrodes.
General description: Methacrylic acid N-hydroxysuccinimide ester(NHS-MA) belongs to the class of reactive monomers known as N-hydroxysuccinimide (NHS) esters. It is commonly used for functionalizing biomolecules through amine-reactive coupling reactions infields such as bioconjugation, protein labeling, and peptide synthesis. It also serves as a crosslinking agent or linker molecule for the conjugation of drugs or targeting ligands to carrier materials.
Packaging: 1, 5 g in glass bottle
Purity 98%
mp 101-105 °C
Storage Temp. 2-8°C
UNSPSC 12162002

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