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trans-1-Acetyl-4-hydroxy-L-proline

ALDRICH/441562 - ≥98%

Synonym: N-Acetyl-L-hydroxyproline

CAS Number: 33996-33-7
Empirical Formula (Hill Notation): C7H11NO4
Molecular Weight: 173.17
EC Number: 251-780-6
MDL Number: MFCD00037339
Linear Formula: C7H11NO4
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-441562-10G 10 g
 $175.00
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application(s) peptide synthesis
assay ≥98%
form powder
InChI 1S/C7H11NO4/c1-4(9)8-3-5(10)2-6(8)7(11)12/h5-6,10H,2-3H2,1H3,(H,11,12)/t5-,6+/m1/s1
InChI key BAPRUDZDYCKSOQ-RITPCOANSA-N
mp 132-133 °C (dec.) (lit.)
optical activity [α]20/D −119°, c = 4 in H2O
Quality Level 100 
reaction suitability reaction type: solution phase peptide synthesis
SMILES string CC(=O)N1C[C@H](O)C[C@H]1C(O)=O
Application: trans-1-Acetyl-4-hydroxy-L-proline can be used:
• In the stereospecific synthesis of 4-fluoroglutamic acid.
• To synthesize molecular targets for von Hippel-Lindau (VHL) E3 ubiquitin ligase.
• As a precursor to synthesize pseudopoly(amino acids) such as poly(trans-4-hydroxy-4-acyl-L-proline ester) and a biodegradable polymer, poly(lactic acid-glycolic acid-4-hydroxyproline).
Packaging: 10 g in glass bottle
Symbol GHS05  GHS05
Signal word Danger
Hazard statements H318
Precautionary statements P280 - P305 + P351 + P338
Hazard Codes Xi
Risk Statements 41
Safety Statements 26-36
RIDADR NONH for all modes of transport
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Purity ≥98%
mp 132-133 °C (dec.) (lit.)
UNSPSC 12352209

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