Dimethyl 2-oxoglutarate
ALDRICH/349631 - 96%
Synonym: Dimethyl α-ketoglutarate
CAS Number: 13192-04-6
Empirical Formula (Hill Notation): C7H10O5
Molecular Weight: 174.15
MDL Number: MFCD00048052
Linear Formula: CH3O2CCH2CH2COCO2CH3
Product Type: Chemical
| assay | 96% |
| bp | 90-95 °C/0.4 mmHg (lit.) |
| density | 1.203 g/mL at 25 °C (lit.) |
| form | liquid |
| functional group | ester |
| ketone | |
| InChI | 1S/C7H10O5/c1-11-6(9)4-3- |
| InChI key | TXIXSLPEABAEHP-UHFFFAOYSA |
| Quality Level | 100  |
| refractive index | n |
| SMILES string | COC(=O)CCC(=O)C(=O)OC |
| Application: | Dimethyl 2-oxoglutarate can undergo cylocondensation with dinucleophiles, such as 1,2-phenylenediamine, 2-aminophenol and 2-aminobenzenethiol to form novel heterocycles. |
| Application: | Dimethyl 2-oxoglutarate may be used to synthesize the conformationally constrained PNA (peptide nucleic acid) -monomer capable of binding thymine in a triplex motif. It may be used in the synthesis of 4-aryl kainic acid analogs, via highly stereoselective Michael addition reaction with nitrostyrene. |
| General description: | Dimethyl 2-oxoglutarate is a key intermediate formed during the Krebs cycle and an important nitrogen transporter in the biological metabolic pathways. The electrochemical behavior of dimethyl-2-oxoglutarate has been investigated by cyclic voltammetry, square wave voltammetry and differential pulse voltammetry using a glassy carbon electrode. |
| Packaging: | 5 g in glass bottle |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | 96% |
| bp | 90-95 °C/0.4 mmHg (lit.) |
| Density | 1.203 g/mL at 25 °C (lit.) |
| Refractive Index | n |
| UNSPSC | 12352100 |