L-tert-Leucine
ALDRICH/269107 - 99%
Synonym: (S)
CAS Number: 20859-02-3
Empirical Formula (Hill Notation): C6H13NO2
Molecular Weight: 131.17
MDL Number: MFCD00064218
Linear Formula: (CH3)3CCH(NH2)CO2H
Product Type: Chemical
| application(s) | peptide synthesis |
| assay | 99% |
| form | powder |
| InChI | 1S/C6H13NO2/c1-6(2,3)4(7) |
| InChI key | NPDBDJFLKKQMCM-SCSAIBSYSA |
| mp | ≥300 °C (lit.) |
| optical activity | [α]20/D −9.5°, c = 3 in H2O |
| optical purity | ee: 99% (GLC) |
| Quality Level | 200  |
| reaction suitability | reaction type: solution phase peptide synthesis |
| SMILES string | CC(C)(C)[C@H](N)C(O)=O |
| Application: | • As a key precursor in the synthesis of a chiral phosphinooxazoline ligand, (S)-tert-butylPHOX. • In the synthesis of chiral copper(II) polymers that can catalyze the kinetic resolution of secondary alcohols by acylation. • In metal-free tandem radical cyclization reactions to synthesize 6-alkyl/acyl phenanthridines. • In the preparation of tert-leucine-derived N-acetylthiazolidinethione auxiliary that provides high levels of diastereoselection in acetate aldol reactions with a variety of aldehydes. |
| General description: | L-tert-Leucine is an amino acid used as a precursor for synthesizing chiral tridentate Schiff base ligands. |
| Packaging: | 5, 25 g in glass bottle |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 1 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | 99% |
| mp | ≥300 °C (lit.) |
| UNSPSC | 12352209 |