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Anti-ABHD15 antibody produced in rabbit

SIGMA/HPA014470 - Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution

Synonym: Anti-AC104564.11 antibody produced in rabbit; Anti-Putative uncharacterized protein LOC116236

Product Type: Chemical

Catalog Number PKG Qty. Price Quantity
45-HPA014470-25UL 25 µL
$294.00
1/EA
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45-HPA014470-100UL 100 µL
$570.00
1/EA
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Immunohistochemistry Immunohistochemical staining of human duodenum shows strong cytoplasmic positivity in glandular cells.
Immunofluorescence Immunofluorescent staining of human cell line A-431 shows localization to nucleoplasm and cytosol.

 

antibody form affinity isolated antibody
antibody product type primary antibodies
biological source rabbit
clone polyclonal
conjugate unconjugated
form buffered aqueous glycerol solution
immunogen sequence TALEDTVDTSRLFRSRSLREFEEALFCHTKSFPISWDAYWDRNDPLRDVDEAAVPVLCICSADDPVCGPPDHTLTTELFHSNPYFFLLLSRHGGHCGFLRQEPLPAWSHEVILESFRALTEFFRTEERIKGLSR
packaging antibody small pack of 25 μL
product line Prestige Antibodies® Powered by Atlas Antibodies
Quality Level 100 
shipped in wet ice
species reactivity human
storage temp. −20°C
technique(s) immunofluorescence: 0.25-2 μg/mL
  immunohistochemistry: 1:50-1:200
Application: All Prestige Antibodies Powered by Atlas Antibodies are developed and validated by the Human Protein Atlas (HPA) project  and as a result, are supported by the most extensive characterization in the industry.

The Human Protein Atlas project can be subdivided into three efforts: Human Tissue Atlas, Cancer Atlas, and Human Cell Atlas. The antibodies that have been generated in support of the Tissue and Cancer Atlas projects have been tested by immunohistochemistry against hundreds of normal and disease tissues and through the recent efforts of the Human Cell Atlas project, many have been characterized by immunofluorescence to map the human proteome not only at the tissue level but now at the subcellular level. These images and the collection of this vast data set can be viewed on the Human Protein Atlas (HPA) site by clicking on the Image Gallery link. We also provide Prestige Antibodies® protocols   and other useful information.
Biochem/physiol Actions: The gene ABHD15 (abhydrolase domain containing 15) encodes a protein that protects cells from apoptosis. Knock-down of ABHD15 causes defects in cell proliferation due to apoptosis. In mice, it has been observed that high-fat diet, fasting, and aging can lead to decreased expression of ABHD15 in adipose tissue.
Disclaimer: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Features and Benefits: Prestige Antibodies® are highly characterized and extensively validated antibodies with the added benefit of all available characterization data for each target being accessible via the Human Protein Atlas portal linked just below the product name at the top of this page. The uniqueness and low cross-reactivity of the Prestige Antibodies® to other proteins are due to a thorough selection of antigen regions, affinity purification, and stringent selection. Prestige antigen controls are available for every corresponding Prestige Antibody and can be found in the linkage section.

Every Prestige Antibody is tested in the following ways:
• IHC tissue array of 44 normal human tissues and 20 of the most common cancer type tissues.
• Protein array of 364 human recombinant protein fragments.
General description: The gene ABHD15 (αβhydrolase domain containing 15) encodes a member of the αβ hydrolase domain (ABHD) proteins that function in lipid synthesis and degradation. It is found to be mainly expressed in brown and white adipose tissue and its expression levels increase during adipogenesis.
Immunogen: Abhydrolase domain-containing protein UNQ6510/PRO21435 precursor
Legal Information: Prestige Antibodies is a registered trademark of Sigma-Aldrich Co. LLC
Linkage: Corresponding Antigen APREST72186 .
Physical form: Solution in phosphate-buffered saline, pH 7.2, containing 40% glycerol and 0.02% sodium azide
RIDADR NONH for all modes of transport
WGK Germany WGK 1
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Storage Temp. −20°C
UNSPSC 12352203

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