Agilent J&W CP-Chirasil Val columns are designed for the separation of optically active compounds, especially amino acids. They have lower bleed levels than other phases with a Tmax of 200°C, isothermally and programmed. Both antipodes of the phase are available. On Chirasil-L-Val, D-amino acids elute before the L-amino acids, while on Chirasil-D-Val this elution order is reversed. This is especially valuable when determining the optical purity of compounds. Selecting the column from which the minor component elutes before the major enantiomer results in the lowest detection levels.