MAGNA nylon membrane by Osmonics has a higher binding capacity (approximately 350µg/cm2) than nitrocellulose membranes and binds a greater range of fragment sizes. It is naturally hydrophilic, eliminating the need for wetting agents that can potentially interfere with biological processes. It wets out quickly and evenly and will never turn hydrophobic during hybridization. UV crosslinking MAGNA nylon is an excellent way to attach nucleic acids. Exposing a nylon membrane to a UV source forms a covalent bond between the membrane and the DNA or RNA and maximizes signal retention after reprobing.
These 0.45µm MAGNA nylon membranes are formed by impregnating an integral support web with nylon, giving the membrane added dimensional strength, which prevents cracking, tearing, curling, and breaking.