- Zorbax SAX and 300SCX columns are based on rugged Zorbax silica
- Stable from pH 2-7
- Provide high efficiency, rapid separations
- Compatible with organic mobile phase modifiers
Zorbax strong ion exchange columns are available as both Strong Anion Exchange (SAX) and Strong Cation Exchange (SCX) columns. Each column is packed with bonded, 5 µm, spherical silica particles for optimum efficiency.
Zorbax Strong Anion Exchange packing has a permanently bonded quaternary amine. A trifunctional organo-silane reagent is used in producing this packing to maximize its stability with aqueous mobile phases. This column is ideal for separation of water-soluble compounds such as aromatic and aliphatic carboxylic acids and sulfonic acids.
Zorbax Strong Cation Exchange packing has 300Å pore size silica particles chemically bonded to an aromatic sulfonic acid group. This column is used for separations of basic, water-soluble compounds and bio-molecules.
Zorbax also has Bio-SCX Series II columns designed for optimized 2D separations of peptides and proteins using LC-MS. This packing is based on ultra-pure 3.5 µm Zorbax silica particles, bonded with a bio-friendly polymer that is functionalized with sulfonic acid groups. This gives strong retention and good peak shape in the ion exchange step of 2D-analysis of peptides and proteins.